胡驰,副研究员,邮箱chihu@cpu.edu.cn。本科就读于同济大学材料科学与工程学院,硕士、博士毕业于英国剑桥大学化学系。于2016年加入中国药科大学,开发了一些列针药物-靶标相互作用、精神活性物质痕量检测的新型分析方法。研究内容获得国家自然科学基金、江苏省自然科学基金资助,研究内容发表于Anal. Chem.等分析化学领域顶级期刊。
研究方向:
1、 毒品吸食人员快速筛查方法;
2、 环境毒品快速检测试剂盒;
3、 疾病相关靶点诊断方法。
代表性科研成果:
[1] Sibo Zhao, Huilin Wen, Yangteng Ou, Minhui Li, Lancheng Wang, Huimin Zhou, Bin Di, Ziyi Yu*, and Chi Hu*, A new design for living cell-based biosensors: microgels with a selectively permeable shell that can harbor bacterial species. Sensors and Actuators B: Chemical, 2021. 334: p. 129648.
[2] Li-li Xu, Cui-cui Li, Lu-yan An, Zhen Dai, Xiao-yi Chen, Qi-dong You*, Chi Hu*, and Bin Di*, Selective apoptosis-inducing activity of synthetic hydrocarbon-stapled SOS1 helix with d-amino acids in H358 cancer cells expressing KRASG12C. European Journal of Medicinal Chemistry, 2020. 185: p. 111844.
[3] Cheng, S., Shen, H., Zhao, S., Zhang, Y., Xu, H., Wang, L., Di, B.*, Xu, L.*, and Hu, C.*, Orally administrated mesoporous silica capped with cucurbit[8]uril complex to combat colitis and improve intestinal homeostasis by targeting gut microbiota. Nanoscale, 2020. 12: p. 15348-15363.
[4] Jia, J., Wen, H., Zhao, S., Wang, L., Qiao, H., Shen, H., Yu, Z., Di, B.*, Xu, L.*, and Hu, C.*, Displacement induced off-on fluorescent biosensor targeting IDO1 activity in live cells. Analytical Chemistry, 2019. 91(23): p. 14943-14950.
[5] Qiao, H., Jia, J., Shen, H., Zhao, S., Chen, E., Chen, W.*, Di, B.*, and Hu, C.*, Capping silica nanoparticles with tryptophan-mediated cucurbit[8]uril complex for targeted intracellular drug delivery triggered by tumor-overexpressed IDO1 enzyme. Advanced Healthcare Materials, 2019. 8(13): p. 1900174.
[6] Qiao, H., Jia, J., Chen, W., Di, B., Scherman, O. A., and Hu, C.*, Magnetic regulation of thermo-chemotherapy from a cucurbit[7]uril-crosslinked hybrid hydrogel. Advanced Healthcare Materials, 2019. 8(2): p. 1801458.