制药与环境工程系

1. Li, Z.#; Wang, Z.#; Chekshin, N.; Qian, S.; Qiao, J. X.; Cheng, P. T.; Yeung, K.-S.; Ewing, W. R.; Yu, J.-Q.* A tautomeric ligand enables directed C‒H hydroxylation with molecular oxygen. Science2021, 372, 1452.  

 2. Li, Z.#; Park, H. S.#; Qiao, J. X.; Yeung, K.-S.; Ewing, W. R.; Yu, J.-Q.* Ligand-enabled C−H hydroxylation with aqueous H2O2 at room temperature. J. Am. Chem. Soc. 2022, 144, 18109.

 3. Li, Z.; Yu, J.-Q.* Ligand-enabled-C(sp3)−H hydroxylation of free amines with aqueous hydrogen peroxide. J. Am. Chem. Soc. 2023, 145, 25948.

 4. Li, Z.; Lin, Z.-Q.; Yan, C.-G.; Duan, W.-L.* Pd-catalyzed asymmetric C−H bond activation for the synthesis of Pstereogenic dibenzophospholes. Organometallics 2019, 38, 3916.

 5. Li, Z.; Duan, W.-L.* Palladium-catalyzed C−H alkenylation of arenes with alkynes: stereoselective synthesis of vinyl chlorides via a 1,4-chlorine migration. Angew. Chem. Int. Ed. 2018, 57, 16041.


李振
教授
院系：suncitygroup太阳集团制药与环境工程系
招生方向：制药工程学、生物与医药
实验室：江宁校区综合研发楼G-237
电子邮箱：zhenli@cpu.edu.cn
办公室：江宁校区综合研发楼G-513
个人简介

李振，教授，博士生导师，中国药科大学“兴药领军学者”

2024.02-今   中国药科大学，教授

2020.08-2024.01   美国Scripps研究所，博士后，师从余金权(Jin-Quan Yu)教授

2016.09-2020.07   扬州大学，博士，师从段伟良教授

2013.09-2016.07   上海应用技术大学与上海有机化学研究所联合培养，硕士，师从段伟良教授


研究方向

1. 药物分子后期修饰：设计高效的化学合成新技术，以实现复杂药物分子的精准修饰，进而优化其生物活性。

2. 药物规模化制备：开发绿色且经济的化学生产新技术，以高效应用于药物合成，从而显著降低生产成本。


承担项目情况


代表性科研成果

1. Li, Z.#; Wang, Z.#; Chekshin, N.; Qian, S.; Qiao, J. X.; Cheng, P. T.; Yeung, K.-S.; Ewing, W. R.; Yu, J.-Q.* A tautomeric ligand enables directed C‒H hydroxylation with molecular oxygen. Science2021, 372, 1452.  

 2. Li, Z.#; Park, H. S.#; Qiao, J. X.; Yeung, K.-S.; Ewing, W. R.; Yu, J.-Q.* Ligand-enabled C−H hydroxylation with aqueous H2O2 at room temperature. J. Am. Chem. Soc. 2022, 144, 18109.

 3. Li, Z.; Yu, J.-Q.* Ligand-enabled-C(sp3)−H hydroxylation of free amines with aqueous hydrogen peroxide. J. Am. Chem. Soc. 2023, 145, 25948.

 4. Li, Z.; Lin, Z.-Q.; Yan, C.-G.; Duan, W.-L.* Pd-catalyzed asymmetric C−H bond activation for the synthesis of Pstereogenic dibenzophospholes. Organometallics 2019, 38, 3916.

 5. Li, Z.; Duan, W.-L.* Palladium-catalyzed C−H alkenylation of arenes with alkynes: stereoselective synthesis of vinyl chlorides via a 1,4-chlorine migration. Angew. Chem. Int. Ed. 2018, 57, 16041.